Summary

Name PLSCR1
Full Name Phospholipid scramblase 1
Synonyms PL scramblase 1, Ca(2+)-dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase, MmTRA1b
Primary ID O15162
Links - -
Type protein
Relations 5
Function May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.; FUNCTION

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation PLSCR1 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
+ up-regulates activity img/direct-activation.png phosphorylation PLSCR1 0.14
Publications: 2 Organism: Homo Sapiens
Tissue: Kidney
+ down-regulates img/direct_inhibition.png phosphorylation PLSCR1 0.14
Publications: 2 Organism: Homo Sapiens