+ |
CSNK2A1 | up-regulates
phosphorylation
|
SHOX |
0.343 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142875 |
Ser106 |
EKREDVKsEDEDGQT |
Homo sapiens |
|
pmid |
sentence |
16325853 |
We show also that casein kinase ii phosphorylates shox on serine 106 efficiently in vitro. S106a shox mutant, defective in phosphorylation, does not activate transcription and fails to induce cell-cycle arrest and apoptosis |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SHOX | up-regulates quantity by expression
transcriptional regulation
|
NPPB |
0.295 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255138 |
|
|
Homo sapiens |
|
pmid |
sentence |
17881654 |
The ability of SHOX to transactivate the NPPB endogenous promoter was demonstrated in luciferase reporter assays using serial deletions of the NPPB promotor region. Binding of SHOX to the NPPB promoter was also demonstrated in vivo by chromatin fixation and immunoprecipitation. We also demonstrate the lack of promoter activation in two SHOX mutants from patients with Leri-Weill syndrome. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |