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Summary
Name
CLDN3
View Modifications
Full Name
Claudin-3
Synonyms
Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2, Rat ventral prostate.1 protein homolog, hRVP1 | C7orf1, CPETR2
Primary ID
O15551
Links
-
-
Type
protein
Relations
1
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
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by mechanism
none
phosphorylation
by effect
none
unknown
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
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Modifications Tables
CLDN3 as Target
Residue
Sequence
Modifier
Effect
Modification
Thr192
PPREKKYtATKVVYS
PRKACA
unknown
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
PRKACA
phosphorylation
CLDN3
0.311
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-137291
Thr192
PPREKKYtATKVVYS
Homo sapiens
pmid
sentence
15905176
Our results suggest that claudin-3 phosphorylation by pka, a kinase frequently activated in ovarian cancer, may provide a mechanism for the disruption of tjs in this cancer.
Publications:
1
Organism:
Homo Sapiens