4.0
Summary
| Name |  PHF1
|
| Full Name | PHD finger protein 1 |
| Synonyms | Protein PHF1, hPHF1, Polycomb-like protein 1, hPCl1 | PCL1 |
| Primary ID | O43189 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Involved in DNA damage response and is recruited at double-strand breaks (DSBs). Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex |
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transcriptional regulation