+ |
PDGFRB | up-regulates
binding
|
NCK2 |
0.598 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-64740 |
|
|
Homo sapiens |
|
pmid |
sentence |
10026169 |
The sh2 domains of grb2, nck, and grb4 all precipitated activated pdgf receptor with similar efficiency. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EGFR | up-regulates
binding
|
NCK2 |
0.408 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-64731 |
|
|
Homo sapiens |
|
pmid |
sentence |
10026169 |
Growth factor binding to receptor protein tyrosine kinases (r-ptks)1 induces their dimerization and trans-phosphorylation, creating docking sites for proteins containing sh2 and ptb protein interaction domains. Nck binds to the pdgf and egfr receptors (figure 3c). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NTRK2 | up-regulates
binding
|
NCK2 |
0.341 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-89764 |
|
|
Homo sapiens |
|
pmid |
sentence |
12074588 |
We identified the nck2 adaptor protein as a novel interaction partner of the active form of trkb. Additionally, we identified three tyrosines in icd-trkb (y694, y695, and y771) that are crucial for this interaction. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |