| + |
ZBTB14 | down-regulates quantity by repression
transcriptional regulation
|
MYC |
0.315 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-220537 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 10080939 |
ZF5, which we have cloned as a transcriptional repressor on the mouse c-myc promoter |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NACC1 | up-regulates activity
binding
|
ZBTB14 |
0.288 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-226443 |
|
|
in vitro |
|
| pmid |
sentence |
| 19121354 |
NAC1 potentiated ZF5 mediated repression in Gal4-DBD fusion transient assays. GST pulldown assays further confirmed proteinprotein interactions between these proteins and NAC1. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
ZBTB14 | up-regulates activity
binding
|
ZBTB14 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-220534 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10080939 |
ZF5, which we have cloned as a transcriptional repressor on the mouse c-myc promoter, has the POZ domain at the amino-terminus and the Kruppel-type zinc finger domain at the carboxy-terminus. We demonstrated that the POZ domain has a function mediating homomeric protein-protein interaction and this interaction requires the zinc finger domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |