Summary

Name GAS2
Full Name Growth arrest-specific protein 2
Synonyms GAS-2
Primary ID O43903
Links - -
Type protein
Relations 3
Function May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png cleavage GAS2 0.428
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png cleavage GAS2 0.428
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png F-actin_assembly 0.7
Publications: 1 Organism: Homo Sapiens