Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273536 |
Tyr104 |
KPEQQMMyAGSKNRL |
Homo sapiens |
Respiratory Smooth Muscle |
pmid |
sentence |
24818551 |
Acetylcholine stimulation also increased GMF-γ phosphorylation at Tyr-104. GMF-γ phosphorylation at this residue was mediated by c-Abl tyrosine kinase. The GMF-γ mutant Y104F (phenylalanine substitution at Tyr-104) had higher association with Arp2 in HASM cells upon contractile activation.Furthermore, expression of mutant Y104F GMF-γ attenuated actin polymerization and contraction in smooth muscle. |
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