3.0
Summary
| Name |  OGAView Modifications |
| Full Name | Protein O-GlcNAcase |
| Synonyms | OGA, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, NCOAT | HEXC, KIAA0679, MEA5, MGEA5 |
| Primary ID | O60502 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | OGA | up-regulates activity 
deglycosylation
|
PFKL | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | OGA | up-regulates activity
deglycosylation
|
PFKM | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | OGA | up-regulates activity
deglycosylation
|
PFKP | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | OGA | down-regulates activity 
deglycosylation
|
G6PD | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | OGA | up-regulates activity
deglycosylation
|
PFK | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |