Relation Results

Summary

Name	CCNT1 View Modifications
Full Name	Cyclin-T1
Synonyms	CycT1, Cyclin-T
Primary ID	O60563
Links	- -
Type	protein
Relations	4
Function	Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II).

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▶Modifications Tables

Relations

Regulator

Mechanism

target

score ℹ

down-regulates activity img/direct_inhibition.png

img/direct_inhibition.png

phosphorylation

0.389

Publications:

1

Organism:

Homo Sapiens

form complex img/form-complex.png

img/form-complex.png

binding

0.964

Publications:

1

Organism:

In Vitro

up-regulates quantity by expression img/indirect-activation.png

img/indirect-activation.png

transcriptional regulation

0.2

Publications:

1

Organism:

Homo Sapiens

up-regulates img/direct-activation.png

img/direct-activation.png

relocalization

0.2

Publications:

1

Organism:

Homo Sapiens