Summary

Name CCNT1
Full Name Cyclin-T1
Synonyms CycT1, Cyclin-T
Primary ID O60563
Links - -
Type protein
Relations 3
Function Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HES1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png relocalization CCNT1 0.2
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding P-TEFb 0.964
Publications: 1 Organism: In Vitro