3.0
Summary
| Name |  EDF1View Modifications |
| Full Name | Endothelial differentiation-related factor 1 |
| Synonyms | EDF-1, Multiprotein-bridging factor 1, MBF1 |
| Primary ID | O60869 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. |
phosphorylation