+ |
SEMA3C | up-regulates activity
binding
|
PLXNA2 |
0.501 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253151 |
|
|
|
|
pmid |
sentence |
19666519 |
Genes encoding the neurovascular guiding molecule semaphorin 3C (SEMA3C) and its receptor plexin A2 (PLXNA2) appear to be regulated directly by GATA6, and both GATA6 mutant proteins failed to transactivate these genes. |
|
Publications: |
1 |
+ |
GATA6 | up-regulates quantity by expression
transcriptional regulation
|
PLXNA2 |
0.248 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253149 |
|
|
|
|
pmid |
sentence |
19666519 |
Genes encoding the neurovascular guiding molecule semaphorin 3C (SEMA3C) and its receptor plexin A2 (PLXNA2) appear to be regulated directly by GATA6, and both GATA6 mutant proteins failed to transactivate these genes. |
|
Publications: |
1 |
+ |
SEMA3A | up-regulates
binding
|
PLXNA2 |
0.853 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-75168 |
|
|
Homo sapiens |
|
pmid |
sentence |
10679438 |
Plexins form stable complexes with neuropilin-1 or -2. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SEMA3B | up-regulates activity
binding
|
PLXNA2 |
0.651 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261812 |
|
|
Homo sapiens |
Endothelial Cell, U-87MG Cell |
pmid |
sentence |
25335892 |
We provide evidence suggesting that, in endothelial cells and glioblastoma cells, plexin-A4 is a required component of both Sema3A and Sema3B receptor complexes and inhibition of its expression nullifies both Sema3A and Sema3B signaling. The specificity for Sema3A or Sema3B is determined by the presence of plexin-A1 in Sema3A receptors and plexin-A2 in Sema3B receptors, and silencing each abrogates signaling by the appropriate semaphorin. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |