Summary

Name GLRA3
Full Name Glycine receptor subunit alpha-3
Synonyms GLRA3_HUMAN |
Primary ID O75311
Links - -
Type protein
Relations 1
Function Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity). Plays an important role in the down-regulation of neuronal excitability (By similarity). Contributes to the generation of inhibitory postsynaptic currents (By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity). Plays a role in cellular responses to ethanol (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png chemical activation GLRA3 0.8
Publications: 1 Organism: Homo Sapiens
Tissue: Retina, Spinal Cord, Brain Stem