Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262663 |
Ser228 |
ELVPSRRsKLRKPKP |
in vitro |
|
pmid |
sentence |
21531210 |
Aurora-C interacts with and phosphorylates the transforming acidic coiled-coil 1 protein. The results demonstrated that TACC1 is phosphorylated by Aurora-C on a serine at position 228. although the patho-physiological meaning of TACC1 phosphorylation by Aurora-C in normal and in malignant somatic cells remains to be fully investigated, our observations suggest that Aurora-C has a role in the later stage of mitosis, when an interaction with TACC1 may be relevant for the correct progression of the cell cycle. |
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