| + |
ATM |
phosphorylation
|
RAD17 |
0.847 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-73520 |
Ser646 |
ETWSLPLsQNSASEL |
Homo sapiens |
|
| pmid |
sentence |
| 10608806 |
We determined a general phosphorylation consensus sequence for atm and identified putative in vitro targets by using glutathione s-transferase peptides as substrates. Putative atm in vitro targets include p95/nibrin, mre11, brca1, rad17, pts, wrn, and atm (s440) itself. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-73524 |
Ser656 |
SASELPAsQPQPFSA |
Homo sapiens |
|
| pmid |
sentence |
| 10608806 |
We determined a general phosphorylation consensus sequence for atm and identified putative in vitro targets by using glutathione s-transferase peptides as substrates. Putative atm in vitro targets include p95/nibrin, mre11, brca1, rad17, pts, wrn, and atm (s440) itself. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
ATR | up-regulates activity
phosphorylation
|
RAD17 |
0.858 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-111248 |
Ser646 |
ETWSLPLsQNSASEL |
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 11687627 |
Here we demonstrate that atr but not atm phosphorylates the human rad17 (hrad17) checkpoint protein on ser(635) and ser(645) in vitro.The rfc-related checkpoint protein rad17, a phosphorylation substrate of atr, is critical for atr-mediated checkpoint signaling and cell survival. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-111252 |
Ser656 |
SASELPAsQPQPFSA |
Homo sapiens |
|
| pmid |
sentence |
| 11687627 |
Here we demonstrate that atr but not atm phosphorylates the human rad17 (hrad17) checkpoint protein on ser(635) and ser(645) in vitro.The rfc-related checkpoint protein rad17, a phosphorylation substrate of atr, is critical for atr-mediated checkpoint signaling and cell survival. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |