4.0
Summary
| Name |  DFFB
|
| Full Name | DNA fragmentation factor subunit beta |
| Synonyms | Caspase-activated deoxyribonuclease, CAD, Caspase-activated DNase, Caspase-activated nuclease, CPAN, DNA fragmentation factor 40 kDa subunit, DFF-40 | CAD, DFF2, DFF40 |
| Primary ID | O76075 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CASP3 | up-regulates 
cleavage
|
DFFB | 0.687 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | DFFA | down-regulates 
binding
|
DFFB | 0.929 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Caspase 3 complex | up-regulates
cleavage
|
DFFB | 0.687 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | DFFB | up-regulates 
|
DNA_fragmentation | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |