Relation Results

Name	SORBS2
Full Name	Sorbin and SH3 domain-containing protein 2
Synonyms	Arg-binding protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin \| ARGBP2, KIAA0777
Primary ID	O94875
Links	- -
Type	protein
Relations	1
Function	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.