3.0
Summary
| Name |  MPZL1View Modifications |
| Full Name | Myelin protein zero-like protein 1 |
| Synonyms | Protein zero-related | PZR |
| Primary ID | O95297 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. |
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phosphorylation
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