3.0
Summary
| Name |  CTDNEP1View Modifications |
| Full Name | CTD nuclear envelope phosphatase 1 |
| Synonyms | Serine/threonine-protein phosphatase dullard | DULLARD |
| Primary ID | O95476 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CTDNEP1 | up-regulates activity 
dephosphorylation
|
LPIN1 | 0.771 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CTDNEP1 | up-regulates
binding
|
BMPR1A | 0.295 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CTDNEP1 | down-regulates 
binding
|
BMPR2 | 0.437 |
| Publications: | 1 | Organism: | Homo Sapiens | |