Summary

Name SEC24B
Full Name Protein transport protein Sec24B
Synonyms SEC24-related protein B |
Primary ID O95487
Links - -
Type protein
Relations 2
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:17499046, PubMed:20427317, PubMed:18843296). Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes (PubMed:17499046, PubMed:18843296).

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Relations

Regulator Mechanism target score ℹ
+ SAR1Aup-regulates quantity img/direct-activation.png binding SEC24B 0.737
Publications: 1
+ SEC24Bform complex img/form-complex.png binding COPII vesicle 0.708
Publications: 1 Organism: Homo Sapiens