| + |
COPII vesicle | up-regulates 
|
Vesicle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265297 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30605680 |
Coat protein complex (COP) II vesicles export newly synthesized secretory proteins from the endoplasmic reticulum (ER) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC24B | form complex 
binding
|
COPII vesicle |
0.709 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265290 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SAR1A | up-regulates quantity 
binding
|
COPII vesicle |
0.71 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265304 |
|
|
|
|
| pmid |
sentence |
| 30605680 |
Biogenesis of COPII vesicles is initiated by the activation of the small guanosine triphosphate (GTP)-binding protein secretion-associated Ras-related protein 1 (Sar1) at specialized subdomains of the ER, called ER exit sites (ERES) or transitional ER (tER). Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. |
|
| Publications: |
1 |
| + |
SEC23B | form complex
binding
|
COPII vesicle |
0.696 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265288 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC31A | form complex
binding
|
COPII vesicle |
0.755 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265292 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC16A | form complex
binding
|
COPII vesicle |
0.716 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265293 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC24A | form complex
binding
|
COPII vesicle |
0.707 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265295 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC24D | form complex
binding
|
COPII vesicle |
0.68 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265291 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC23A | form complex
binding
|
COPII vesicle |
0.789 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265289 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC13 | form complex
binding
|
COPII vesicle |
0.841 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265296 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC24C | form complex
binding
|
COPII vesicle |
0.683 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265294 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC31B | form complex
binding
|
COPII vesicle |
0.655 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265287 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 30605680 |
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
COPII vesicle