Summary

Name CFB
Full Name Complement factor B
Synonyms C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B | BF, BFD
Primary ID P00751
Links - -
Type protein
Relations 5
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png cleavage CFB 0.796
Publications: 2 Organism: Homo Sapiens
Tissue: Blood
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CFB 0.2
Publications: 1 Organism: Homo Sapiens
Tissue: L-6 Myoblast Cell
+ down-regulates activity img/direct_inhibition.png binding CFB 0.497
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding C3 convertase complex (C3bBb) 0.903
Publications: 1 Organism: Homo Sapiens
Tissue: Blood