Summary

Name LDLR
Full Name Low-density lipoprotein receptor
Synonyms LDL receptor
Primary ID P01130
Links - -
Type protein
Relations 4
Function Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png chemical activation LDLR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LDLR 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LDLR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LDLR 0.14
Publications: 1 Organism: Homo Sapiens