3.0
Summary
| Name |  gH
|
| Full Name | Envelope glycoprotein H |
| Synonyms | gH | |
| Primary ID | P03231 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Pathways | EBV infection |
| Function | The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. The heterodimer gH/gL targets also host EPHA2 to promote viral entry. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | gH | form complex 
binding
|
EBV gH:gL:gp42 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | EBV infection | |||