4.0
Summary
| Name |  ATP1B1
|
| Full Name | Sodium/potassium-transporting ATPase subunit beta-1 |
| Synonyms | Sodium/potassium-dependent ATPase subunit beta-1 | ATP1B |
| Primary ID | P05026 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | hsa-miR-29a-5p | down-regulates quantity by repression 
post transcriptional regulation
|
ATP1B1 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NR3C1 | down-regulates quantity by repression
transcriptional regulation
|
ATP1B1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | WFS1 | up-regulates quantity 
binding
|
ATP1B1 | 0.397 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | RNF183 | down-regulates quantity by destabilization
polyubiquitination
|
ATP1B1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NR3C2 | down-regulates quantity by repression 
transcriptional regulation
|
ATP1B1 | 0.238 |
| Publications: | 1 | Organism: | Homo Sapiens | |