| + | 
              
              TGFB1 | down-regulates quantity by repression   
              transcriptional regulation
               | 
              SFTPB | 
              
              0.282 | 
                    
						
							
								
									| Identifier | 
									Residue | 
									Sequence | 
									Organism | 
									Cell Line | 
								 
							
								
								
									| SIGNOR-254170 | 
									 | 
									 | 
									Homo sapiens | 
									Lung Epithelial Cell | 
								
								 
									| pmid | 
									sentence | 
								 
								 
									| 18003659 | 
								
									TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells.  | 
								 
						 
                     | 
              
               
			   
					| Publications: | 
					
				
					1 | 
					Organism: | 
							Homo Sapiens | 
				
              | + | 
              
              FOXA1 | up-regulates quantity by expression   
              transcriptional regulation
               | 
              SFTPB | 
              
              0.284 | 
                    
						
							
								
									| Identifier | 
									Residue | 
									Sequence | 
									Organism | 
									Cell Line | 
								 
							
								
								
									| SIGNOR-254171 | 
									 | 
									 | 
									Homo sapiens | 
									Lung Epithelial Cell | 
								
								 
									| pmid | 
									sentence | 
								 
								 
									| 18003659 | 
								
									TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. Repression is mediated by SMAD3 through interactions with NKX2.1 and FOXA1, two key transcription factors that are positive regulators of SpB transcription. | 
								 
						 
                     | 
              
               
                    
						
							
								
									| Identifier | 
									Residue | 
									Sequence | 
									Organism | 
									Cell Line | 
								 
							
								
								
									| SIGNOR-254181 | 
									 | 
									 | 
									Homo sapiens | 
									 | 
								
								 
									| pmid | 
									sentence | 
								 
								 
									| 12161428 | 
								
									 A homeodomain and a forkhead transcription factor, NKX2.1 and HNF-3, respectively, are known activators of Sp-B transcription | 
								 
						 
                     | 
              
               
			   
					| Publications: | 
					
				
					2 | 
					Organism: | 
							Homo Sapiens | 
				
              | + | 
              
              NKX2-1 | up-regulates quantity by expression   
              transcriptional regulation
               | 
              SFTPB | 
              
              0.475 | 
                    
						
							
								
									| Identifier | 
									Residue | 
									Sequence | 
									Organism | 
									Cell Line | 
								 
							
								
								
									| SIGNOR-254172 | 
									 | 
									 | 
									Homo sapiens | 
									Lung Epithelial Cell | 
								
								 
									| pmid | 
									sentence | 
								 
								 
									| 18003659 | 
								
									TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. Repression is mediated by SMAD3 through interactions with NKX2.1 and FOXA1, two key transcription factors that are positive regulators of SpB transcription. | 
								 
						 
                     | 
              
               
			   
					| Publications: | 
					
				
					1 | 
					Organism: | 
							Homo Sapiens |