+ |
FOXA1 | up-regulates quantity by expression
transcriptional regulation
|
SFTPB |
0.287 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254171 |
|
|
Homo sapiens |
Lung Epithelial Cell |
pmid |
sentence |
18003659 |
TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. Repression is mediated by SMAD3 through interactions with NKX2.1 and FOXA1, two key transcription factors that are positive regulators of SpB transcription. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254181 |
|
|
Homo sapiens |
|
pmid |
sentence |
12161428 |
A homeodomain and a forkhead transcription factor, NKX2.1 and HNF-3, respectively, are known activators of Sp-B transcription |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
+ |
NKX2-1 | up-regulates quantity by expression
transcriptional regulation
|
SFTPB |
0.486 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254172 |
|
|
Homo sapiens |
Lung Epithelial Cell |
pmid |
sentence |
18003659 |
TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. Repression is mediated by SMAD3 through interactions with NKX2.1 and FOXA1, two key transcription factors that are positive regulators of SpB transcription. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TGFB1 | down-regulates quantity by repression
transcriptional regulation
|
SFTPB |
0.286 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254170 |
|
|
Homo sapiens |
Lung Epithelial Cell |
pmid |
sentence |
18003659 |
TGF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |