Summary

Name Host translation inhibitor nsp1
Full Name Host translation inhibitor nsp1
Synonyms pp1ab, ORF1ab polyprotein |
Primary ID P0C6X7-PRO_0000037309
Links - -
Type protein
Relations 4
Pathways SARS-CoV ATTACHMENT AND ENTRY, SARS-CoV CYTOKINE STORM, SARS-CoV INFLAMMATORY RESPONSE, SARS-CoV INNATE RESPONSE TO dsRNA, SARS-CoV STRESS GRANULES
Function Multifunctional protein involved in the transcription and replication of viral RNAs. Contains the proteinases responsible for the cleavages of the polyprotein.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/indirect_inhibition.png JUN 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV CYTOKINE STORM
+ down-regulates activity img/indirect_inhibition.png STAT1 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV CYTOKINE STORM
+ down-regulates activity img/indirect_inhibition.png IRF7 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV CYTOKINE STORM
+ down-regulates activity img/indirect_inhibition.png IRF3 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:SARS-CoV ATTACHMENT AND ENTRY, SARS-CoV INFLAMMATORY RESPONSE, SARS-CoV INNATE RESPONSE TO dsRNA, SARS-CoV STRESS GRANULES