Name SLC2A2
Full Name Solute carrier family 2, facilitated glucose transporter member 2
Synonyms Glucose transporter type 2, liver, GLUT-2 | GLUT2
Primary ID P11168
Links - -
Type protein
Relations 6
Inhibitors streptozocin
Function Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.


Modifications Tables


Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation SLC2A2 0.14
Publications: 3 Organism: Chlorocebus Aethiops
+ down-regulates quantity img/direct_inhibition.png chemical inhibition SLC2A2 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SLC2A2 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional activation SLC2A2 0.22
Publications: 1 Organism: Mus Musculus