Relation Results

Name	IFI30
Full Name	Gamma-interferon-inducible lysosomal thiol reductase
Synonyms	Gamma-interferon-inducible protein IP-30, Legumaturain \| GILT, IP30
Primary ID	P13284
Links	- -
Type	protein
Relations	2
Pathways	MHC class II antigen presentation
Function	Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation (By similarity).