Summary

Name CYBA
Full Name Cytochrome b-245 light chain
Synonyms Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox |
Primary ID P13498
Links - -
Type protein
Relations 4
Function Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CYBA 0.2
Publications: 1 Organism: In Vitro
+ up-regulates img/direct-activation.png phosphorylation CYBA 0.2
Publications: 1 Organism: In Vitro
+ form complex img/form-complex.png binding Phagocyte NADPH oxidase complex 0.74
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding CYBA 0.783
Publications: 1 Organism: Homo Sapiens