3.0
Summary
| Name |  PRKAR2AView Modifications |
| Full Name | cAMP-dependent protein kinase type II-alpha regulatory subunit |
| Synonyms | KAP2_HUMAN | PKR2, PRKAR2 |
| Primary ID | P13861 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Inhibitors | 3',5'-cyclic AMP |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKAR2A | up-regulates activity 
phosphorylation
|
PRKAR2A | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PJA2 | down-regulates quantity by destabilization 
polyubiquitination
|
PRKAR2A | 0.333 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKAR2A | down-regulates activity
binding
|
PRKACA | 0.87 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKAR2A | down-regulates activity
binding
|
PRKACB | 0.89 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PDE4DIP | up-regulates
binding
|
PRKAR2A | 0.464 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | 3',5'-cyclic AMP | down-regulates activity
chemical inhibition
|
PRKAR2A | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |