Summary

Name PRKAR2A
Full Name cAMP-dependent protein kinase type II-alpha regulatory subunit
Synonyms KAP2_HUMAN | PKR2, PRKAR2
Primary ID P13861
Links - -
Type protein
Relations 6
Inhibitors 3',5'-cyclic AMP
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

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▶Modifications Tables

Relations

Regulator Mechanism target score ℹ
+ PRKAR2Aup-regulates activity img/direct-activation.png phosphorylation PRKAR2A 0.2
Publications: 1 Organism: In Vitro
+ 3',5'-cyclic AMPdown-regulates activity img/direct_inhibition.png chemical inhibition PRKAR2A 0.8
Publications: 1 Organism: Homo Sapiens
+ PRKAR2Adown-regulates activity img/direct_inhibition.png binding PRKACA 0.871
Publications: 1 Organism: Homo Sapiens
+ PDE4DIPup-regulates img/direct-activation.png binding PRKAR2A 0.464
Publications: 1 Organism: Homo Sapiens
+ PRKAR2Adown-regulates activity img/direct_inhibition.png binding PRKACB 0.891
Publications: 1 Organism: Homo Sapiens
+ PJA2down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination PRKAR2A 0.333
Publications: 1 Organism: Homo Sapiens