Summary

Name HSD17B1
Full Name 17-beta-hydroxysteroid dehydrogenase type 1
Synonyms 17-beta-hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 28C member 1 | E17KSR, EDH17B1, EDH17B2, EDHB17, SDR28C1
Primary ID P14061
Links - -
Type protein
Relations 2
Function Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:8994190). Also has 20-alpha-HSD activity. Uses preferentially NADH.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png chemical modification estrone 0.8
Publications: 1 Organism: In Vitro
+ up-regulates quantity img/direct-activation.png chemical modification 17beta-estradiol 0.8
Publications: 1 Organism: In Vitro