3.0
Summary
| Name |  CREB1
|
| Full Name | Cyclic AMP-responsive element-binding protein 1 |
| Synonyms | CREB-1, cAMP-responsive element-binding protein 1 | |
| Primary ID | P16220-1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CEBPB | up-regulates activity 
binding
|
CREB1 (isoform 1) | 0.578 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |