3.0
Summary
| Name |  H1-2View Modifications |
| Full Name | Histone H1.2 |
| Synonyms | Histone H1c, Histone H1d, Histone H1s-1 | H1F2 |
| Primary ID | P16403 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ITCH | up-regulates activity 
polyubiquitination
|
H1-2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKDC | down-regulates activity 
phosphorylation
|
H1-2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RNF168 | down-regulates
polyubiquitination
|
H1-2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RNF8 | down-regulates
polyubiquitination
|
H1-2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | H1-2 | down-regulates activity
binding
|
TP53BP1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |