| + |
GH1 | up-regulates 
binding
|
PRLR |
0.762 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-35575 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 7984244 |
Hprl does not bind to the hgh receptor, but hgh binds to both the hghr and hprlr, and mutagenesis studies have shown that the receptor-binding sites on hgh overlap. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PRLR | down-regulates quantity by repression 
transcriptional regulation
|
FOXO3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254187 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 17975019 |
We also show that activation of RS represses the expression of the transcription factor Forkhead box O3 (FOXO3) and that of the enzyme galactose-1-phosphate uridyltransferase (Galt), two proteins known to be essential for normal follicular development. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
PRL | up-regulates
binding
|
PRLR |
0.922 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-72810 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10585417 |
Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor (prlr). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
PRLR
- 
- 