Summary

Name RHOQ
Full Name Rho-related GTP-binding protein RhoQ
Synonyms Ras-like protein TC10, Ras-like protein family member 7A | ARHQ, RASL7A, TC10
Primary ID P17081
Links - -
Type protein
Relations 4
Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding EXOC7 0.62
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation RHOQ 0.2
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates img/indirect-activation.png SLC2A4 0.445
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png RHOQ 0.291
Publications: 1 Organism: Homo Sapiens