3.0
Summary
| Name |  TPH1View Modifications |
| Full Name | Tryptophan 5-hydroxylase 1 |
| Synonyms | Tryptophan 5-monooxygenase 1 | TPH, TPRH, TRPH |
| Primary ID | P17752 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | Catecholamine metabolism |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKACA | up-regulates activity 
phosphorylation
|
TPH1 | 0.355 |
| Publications: | 1 | Organism: | In Vitro | |
| + | TPH1 | down-regulates quantity 
chemical modification
|
tryptophan | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TPH1 | up-regulates quantity
chemical modification
|
5-hydroxy-L-tryptophan | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Catecholamine metabolism | |||