+ |
testosterone | up-regulates activity
chemical activation
|
SRD5A1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251532 |
|
|
Homo sapiens |
|
pmid |
sentence |
15861399 |
Testosterone is the predominant circulating androgen in mammals and is converted to dihydrotestosterone (DHT) by 5α-reductase in certain tissues of the male urogenital tract, skin, and other target cells. DHT binds with highest affinity to AR and together with testosterone promotes AR transcriptional activity thereby ensuring the development and maintenance of male reproductive functions. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SRD5A1 | up-regulates quantity
chemical modification
|
17beta-hydroxy-5alpha-androstan-3-one |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251534 |
|
|
Homo sapiens |
|
pmid |
sentence |
15861399 |
Testosterone is the predominant circulating androgen in mammals and is converted to dihydrotestosterone (DHT) by 5α-reductase in certain tissues of the male urogenital tract, skin, and other target cells. DHT binds with highest affinity to AR and together with testosterone promotes AR transcriptional activity thereby ensuring the development and maintenance of male reproductive functions. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |