4.0
Summary
| Name |  LIG1View Modifications |
| Full Name | DNA ligase 1 |
| Synonyms | DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1 |
| Primary ID | P18858 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CDK2 | up-regulates activity 
phosphorylation
|
LIG1 | 0.457 |
| Publications: | 3 | Organism: | Homo Sapiens | |
| + | CSNK2A1 | up-regulates activity
phosphorylation
|
LIG1 | 0.34 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDK1 | up-regulates activity
phosphorylation
|
LIG1 | 0.365 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | miR-325 | down-regulates quantity by destabilization 
post transcriptional regulation
|
LIG1 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |