Summary

Name CXCL3
Full Name C-X-C motif chemokine 3
Synonyms GRO-gamma(1-73), Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta | GRO3, GROG, SCYB3
Primary ID P19876
Links - -
Type protein
Relations 1
Pathways iCAF signaling in PDAC, Chemokines PDAC
Function Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding CXCR2 0.713
Publications: 1 Organism: Homo Sapiens