Relation Results

Summary

Name HLA-DPA1
Full Name HLA class II histocompatibility antigen, DP alpha 1 chain
Synonyms DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1 | HLA-DP1A, HLASB
Primary ID P20036
Links - -
Type protein
Relations 1
Function Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recog ...
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Type: Score: Layout: SPV 
0.265RFX complexHLA-DPA1

Relations

Regulator
Mechanism
target
score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HLA-DPA1 0.265
Identifier Residue Sequence Organism Cell Line
SIGNOR-253995 in vitro
pmid sentence
The RFX complex is comprised of three proteins – RFX5, RFXB, and RFXAP – all of which are required for expression of MHCII genes|In our current studies, we have utilized electrophoretic mobility shift assays to characterize the DNA binding of the RFX5(1–330)2•RFXAP•RFXB complex to the proximal regulatory region from the HLA-DRα gene to gain insight into the DNA binding properties of the RFX complex
Publications: 1 Organism: In Vitro
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