| + |
NDRG1 | up-regulates 
binding
|
RAB4A |
0.328 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-157697 |
|
|
Homo sapiens |
Breast Cancer Cell, Prostate Gland Cancer Cell |
| pmid |
sentence |
| 17786215 |
In this report evidence is provided that ndrg1 is a rab4a effector protein that localizes to perinuclear recycling/sorting vesicles in the trans golgi network by binding to phophatidylinositol 4-phosphate and is involved in recycling of e-cadherin. This is the first demonstration providing evidence that ndrg1 is a rab4a effector recruiting to recycling/sorting endosomes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB4A | up-regulates activity
binding
|
RUFY1 |
0.666 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261280 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20534812 |
Here, we have demonstrated that Rab14 interacts with RUFY1, previously identified as a Rab4 effector, and is required for RUFY1 recruitment onto endosomes and efficient recycling of Tfn.|We also found that enlargement of early endosomes mediated by RUFY1 requires its interaction with Rab4 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB4A | form complex 
binding
|
Early Endosome |
0.435 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260617 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19924646 |
The Rab proteins primarily localized to the EE include Rab5 and Rab4, which regulate distinct early endocytic events. In addition to these two Rab proteins, some of the other less well-characterized Rabs at the EE include Rab10 , Rab14 , Rab21 and Rab22 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
RAB4A
- 
- 