Summary

Name RAB4A
Full Name Ras-related protein Rab-4A
Synonyms RAB4A_HUMAN | RAB4
Primary ID P20338
Links - -
Type protein
Relations 3
Function Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding Early Endosome 0.436
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding RAB4A 0.328
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding RUFY1 0.667
Publications: 1 Organism: Homo Sapiens