Summary

Name ATP6V1C1
Full Name V-type proton ATPase subunit C 1
Synonyms V-ATPase subunit C 1, Vacuolar proton pump subunit C 1 | ATP6C, ATP6D, VATC
Primary ID P21283
Links - -
Type protein
Relations 2
Function Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity). {ECO:0000250|UniProtKB:P21282, ECO:0000250|UniProtKB:P31412, ECO:0000269|PubMed:33065002}.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding V-ATPase 0.774
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ATP6V1C1 0.2
Publications: 1