Summary

Name GLRA2
Full Name Glycine receptor subunit alpha-2
Synonyms GLRA2_HUMAN |
Primary ID P23416
Links - -
Type protein
Relations 2
Function Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Plays a role in cellular responses to ethanol (PubMed:23895467).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png chemical activation GLRA2 0.8
Publications: 1 Organism: Homo Sapiens
Tissue: Retina, Spinal Cord, Brain Stem
+ up-regulates activity img/direct-activation.png chemical activation GLRA2 0.8
Publications: 1 Organism: Xenopus Laevis