| + |
glycine | up-regulates activity
chemical activation
|
GLRA2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264981 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18721822 |
The glycine receptor chloride channel (GlyR), a member of the pentameric Cys-loop ion channel receptor family, mediates inhibitory neurotransmission in the spinal cord, brainstem and retina. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Retina, Spinal Cord, Brain Stem |
| + |
ethanol | up-regulates activity
chemical activation
|
GLRA2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258496 |
|
|
Xenopus laevis |
Oocyte |
| pmid |
sentence |
| 8700149 |
Pharmacologically relevant concentrations of ethanol (10-200 mM) reversibly potentiated the glycine receptor function in all receptors. Ethanol potentiation depended on the glycine concentration used, with decreased potentiation observed at higher glycine concentrations. |
|
| Publications: |
1 |
Organism: |
Xenopus Laevis |