| + |
SREBF2 | up-regulates quantity by expression
transcriptional regulation
|
PON1 |
0.297 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255224 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20728021 |
we conclude that quercetin exhibits its antiatherogenic property by eliciting the translocation of the mature SREBP2 from endoplasmic reticulum to the nucleus, where it binds to SRE-like sequence in the PON1 promoter and up-regulates PON1 gene transcription and PON1 activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
PON1 |
0.268 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255212 |
|
|
Homo sapiens |
Hep-G2 Cell |
| pmid |
sentence |
| 15380450 |
These data suggest that Sp1 acts as a positive regulator of PON1 transcription, and that an interaction between Sp1 and PKC is a key mechanism for the effect of Sp1 on PON1 transcription. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |