+ |
RFX complex | up-regulates quantity by expression
transcriptional regulation
|
HLA-DMA |
0.334 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253993 |
|
|
in vitro |
|
pmid |
sentence |
11258423 |
The RFX complex is comprised of three proteins – RFX5, RFXB, and RFXAP – all of which are required for expression of MHCII genes|In our current studies, we have utilized electrophoretic mobility shift assays to characterize the DNA binding of the RFX5(1–330)2•RFXAP•RFXB complex to the proximal regulatory region from the HLA-DRα gene to gain insight into the DNA binding properties of the RFX complex |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
CIITA | up-regulates quantity by expression
transcriptional regulation
|
HLA-DMA |
0.413 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254004 |
|
|
|
|
pmid |
sentence |
9300700 |
The class II transactivator (CIITA) is a highly specific transcription factor that activates only genes known to be involved in the class II MHC processing pathway, including class II MHC, invariant chain, and HLA-DMA/B genes. |
|
Publications: |
1 |