Summary

Name HLA-DMA
Full Name HLA class II histocompatibility antigen, DM alpha chain
Synonyms MHC class II antigen DMA, Really interesting new gene 6 protein | DMA, RING6
Primary ID P28067
Links - -
Type protein
Relations 2
Function Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HLA-DMA 0.334
Publications: 1 Organism: In Vitro
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HLA-DMA 0.413
Publications: 1